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KO for cancer? Combination therapy packs one-two punch, Duke researchers find
UniversityTech: Attacking a protein could make melanoma tumors vulnerable to chemotherapy.
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SunTech Medical opens manufacturing facility in China
Developer of blood pressure device technology also has plants in Triangle, U.K. and Hong Kong.
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NCSU names University of Illinois scientist to lead N.C. Research Campus effort
May Ann Lila to take director’s role N.C. State Fruit and Vegetable Science Institute on Kannapolis campus. NCSU plans to staff effort with 60 new jobs, including 12 faculty slots.
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Robots with scalpels – first steps toward autonomous mechanical surgeries
UniversityTech: Duke engineers used a novel 3-D ultrasound technology to guide the actions of a rudimentary tabletop robot.
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Formal opening nears for N.C. Research Campus
NCRC’s director of business development says collaboration is already under way among future tenants. Plus, billionaire David Murdock and his management team continue to recruit more tenants. NCRC to offer a sneak preview of campus in networking event along with LTW.
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Pozen’s revenue forecast tops Wall Street expectations
Drug maker sees bigger sales of recently approved migraine drug.
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Genome wrestling? Genetic 'tag team' keeps cells on cycle
UniversityTech: Cascades of interdependent genes coordinate timing for the cell, Duke genetics researchers find.
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Quintiles acquires Boston consulting firm
The deal is the latest move by the global contract research organization to expand its consulting business.
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Coalition to Transform Clinical Trials names executive board
UniversityTech: FDA teams up with Duke to form group, which is public-private partnership.
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Targacept receives $500,000 milestone payment from GSK
Biopharmaceutical firm designates lead compound in smoking cessation program.
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ParagonDx receives FDA approval for blood thinner genetics test
Genotyping test identifies if patients are at risk of negative reaction to warfarin.
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UCLA researchers induce mice cells to mimic embryonic stem cells
Stem Cells journal to publish study that reports on advance made to produce patient-specific stem cells for use in combating diseases.
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Researchers identify new cell targets for preventing growth of breast cancer, other tumors
UniversityTech: Targeting blood vessel formation, or angiogenesis, promises to be less toxic than the standard chemotherapy approach that kills cancer cells and normal cells alike.
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3-D ultrasound could improve stroke diagnosis and care, Duke researchers report
UniversityTech: System sees blood vessels in brain in real time. The 3-D ultrasound has the benefit of being less expensive and faster than the traditional methods of assessing blood flow in the brain – MRI or CT scanning.
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RTP startup Entegrion wins FDA approval to sell bandages to consumers
Bandages are designed to control bleeding. They will be sold via prescription and over counter.
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Ca$hing in – Pozen receives $20M payment from GSK for migraine drug
FDA’s approval of Treximet triggers another big payment to Chapel Hill drug development firm.
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When It Comes to Genome, It’s Often Nurture Over Nature
UniversityTech: NCSU Geneticists report environmental factors such as lifestyle, geography have impact on genes.
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GlaxoSmithKline to Buy Massachusetts-Based Sirtis for $720M
Startup, which went public last May, is focused on enzyme research.
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N.C. State Researcher's HIV Findings May Lead to New Treatment Strategies
UniversityTech: Virus actually can cause body’s immune system to help increase replication.
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UNC-CH, Hamner Institutes Team Up for Research, Commercialization Efforts
Several UNC departments will collaborate with Hamner in seeking therapies to combat cancer, respiratory diseases. Organizations will share in costs of developing products and in ownership.
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N.C. Biotechnology Center Names Award after Community College President
Martin Lancaster, who is retiring April 30, is honored for role in helping build state's biotech sector.
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Health Care Is Undergoing a ‘Metamorphosis,’ FDA Commissioner Says
A convergence of technology presents opportunities to transform how illness, diseases are detected and treated, Andrew von Eschenbach tells SAS conference. In interview, he says challenge is how leaders will capitalize on chance to ‘shape’ how health care ‘butterfly’ is developed.
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FDA Approval of Migraine Drug Could Mean Many Big Paydays for Pozen
GSK will pay Pozen millions more in a milestone payment plus royalties when Treximet goes on sale in May. One analyst sees Pozen earning $200 million a year in royalties.
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Molecule Delivery Method Improves Embryonic Stem Cell Differentiation, Georgia Tech-Emory Researchers Say
UniversityTech: ‘The importance of these findings is that we’ve shown that biomaterial-based approaches to regulate stem cell microenvironments can significantly improve differentiation methods,’ lead professor says.
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N.C. Biofuels Center Awards 15 Alternative Projects $2.5M in Grants
Wide variety pr projects across state receive 'jump start' funding.
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Sampson County Lands $200M Power Plant That Will Burn Poultry Litter
Fibrowatt says facility will create 100 jobs, generate enough electricity to power 40,000 homes for a year. County will provide $2.5M in tax incentives.
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Fighting AIDS: Leading HIV Researchers to Collaborate on Vaccine Development
UniversityTech: Center for HIV/AIDS Vaccine Immunology at Duke, International AIDS Vaccine Initiative plan to "lay the groundwork for new vaccine approaches."
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Oh, What a Relief for Pozen, GSK – FDA Approves Migraine Drug; Pozen Shares Surge
After years-long battle, Chapel Hill-based pharmaceutical firm and GlaxoSmithKline prevail. Treximet can now go on sale. News sends Pozen shares up 37%.
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N.C. Biotech Training Group Changes Name
NCBIOIMPACT is new name for consortium involved in biotech worker training programs.
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Exercise May Lead to Faster Prostate Tumor Growth, Duke Researchers Report
UniversityTech: Findings could lead to design of drugs to treat prostate and other cancers.
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Duke, Blue Cross Team Up to Expand Physician Assistant Program
With financial support from Duke Endowment, university plans to graduate more PAs to help boost primary care.
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PPD to Establish Clinical Research Operation at N.C. Research Campus
The pharmaceutical, research firm plans to create up to 300 jobs at the complex being built by billionaire David Murdock.
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Duke Medical Center Lands Record Gift – $50M – from Duke Endowment
Duke University Medical Center plans to build a medical education facility and a new pediatric inpatient treatment facility with the money from the Charlotte-based endowment.
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N.C. Research Campus Lands another Tennant
Billionaire founder Murdock to be on hand for announcement.
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Our Campaign Debate About Health Care Is Missing the Point
Analysis: It’s a delusion to think we can expand access to the existing system without breaking the bank, regardless of whether we end up adopting the Democratic or Republican solutions now under discussion.
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Knowing Doctor's Financial Interest Doesn't Deter Clinical Trial Participants
UniversityTech: A patient's willingness to participate in a clinical trial may be unaffected by the disclosure of a researcher's financial interests in the study, unless the amount of money a researcher stands to earn depends on the results of the trial, Duke, Wake Forest, johns Hopkins researchers say.
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BioDelivery Sciences Receives $2.5 Million at Milestone
Meda AB Files for European Approval of BEMA™ Fentanyl
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Genomic Profiling of Breast Tumors Might Determine Prognosis, Treatment
UniversityTech: Researchers looked at almost 1000 breast tumor samples, and corresponding patient data, and applied existing technology to assess clinical characteristics and make predictions of recurrence based on them.
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Poor Sleep More Dangerous for Women, Duke Study Confirms
UniversityTech: Poor sleep is associated with greater psychological distress and higher levels of biomarkers associated with elevated risk of heart disease and type 2 diabetes, researchers report.
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Predictors of Sudden Cardiac Death Change Following Heart Attack
UniversityTech:
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Step Aside, Heels - This Poll Ranks Duke No. 1 in Basketball
Americans tell the Harris Poll their favorite men's basketball team is Duke and the Blue Devils ascend to No. 1 over North Carolina
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GeoVax Names CryoLife Co-Founder as CEO
Robert McNally, who has been on GeoVax board, replaces Don Hildebrand, who remains board chairman. GeoVax is focused on AIDS vaccine development.
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UNC, Harvard Researchers Develop Inhaled TB Vaccine
UniversityTech: ‘The real advantage is that this vaccine does not need to be refrigerated. It also doesn’t require needles, syringes and water like the injectable vaccine, and administering it is as easy as breathing in, making it ideal for use in developing countries,’ lead UNC researcher says.
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RTI Wins $6.9M Federal Forensic Labs Contract
Triangle firm will seek to expand National Forensic Laboratory Information System, which its researchers helped create in 1997.
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Misys Healthcare To Merge with Allscripts; Triangle Entrepreneur in Both Companies’ Predecessors Quits
U.K.-based parent of Misys healthcare to pay $330 million in order to create joint venture. Company will be based in Chicago. Allscripts acquired Cary-based A4 Health Solutions two years ago. A4’s John McConnell resigns from Allscripts board.
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Alimera Sciences Takes Larger Stake in Eye Treatment Drug
Venture-backed drug startup could pay Australian firm an additional $78 million. Intersouth is an investor in Alimera.
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BD to Build in Wilson, Expand in Durham
Medical technology firm will add 274 jobs and invest $134.7 million in projects. BD will receive nearly $4M in state incentives.
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Oregon Biotech Firm Acquires RTP-Based Ercole Biotech
AVI BioPharma pays $7.5M in stock, assumes $1.5M in debt in deal. Firms are partners in drug development.
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Trimeris Co-Founder, AIDS Pioneer Dani Bolognesi Launches New Venture
Teaming up with former Trimeris CFO Robert Bonczek, Bolognesi is chairman and CEO for b3bio. Startup will be housed at Hamner Institute incubator.
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$2 Million Gift from Billionaire Murdock to Fund New NCSU Research Efforts
With $1 million matching grant, State will create three professorships to focus on improving food nutrition.
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Biotechnology Firm Affinergy Lands More than $3M in Grants
$2 million phase two award targets use of ‘linkers’ to improve patient healing process.
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Electronic Data Capture Trials Surge at Quintiles
Paper or PC? More and more companies are going EDC for clinical information, CRO says.
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GSK Faces Barrage of Criticism in U.K. over Anti-Depressant
UPDATE: While drug giant won’t be prosecuted for ‘happy pill,’ mental health group calls for reform. British media is buzzing with the news. Financial Times joins calls for change. GSK denies any wrongdoing.
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Forget to Take Your Medication? High-Tech Necklace May Be Answer
UniversityTech: Georgia Tech researchers have developed a necklace that monitors prescription adherence – and reminds people if they forget pills or err in dosage.
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What a Pain: Costly Placebo Works Better than a Cheap One
UniversityTech: Expectations of quality color how people perceive pain, Duke researcher reports.
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UNC Researchers May Have Found Key to Cystic Fibrosis
UniversityTech: Discovery of molecular mechanism could lead to corrective treatments.
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Virtual Teamwork Training Could Boost Healthcare Safety
Virtual Heroes teams up with Duke Medical Center for 3DiTeams, a 3D program funded by Pentagon, Agency for Healthcare Research and Quality.
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Generic Competition Cuts Deeply into Profits, Salix Says
Raleigh-based pharmaceutical firm takes $34.6 million charge, ends up with quarterly, annual loss.
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Pfizer to Acquire Drug Development Company Serenex
Durham-based company is focused on fighting cancer with technology developed at Duke University. Financial backers include Intersouth. Serenex had raised $81M in venture capital.
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Hamner Institutes Wins $655,367 Federal Grant
Researchers will study toxicity of new natural gas-based jet fuel.
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New Light-Rail Zips Fans to Bobcats Arena
The men's games start Wednesday night in the 63rd Annual CIAA Basketball Tournament in Charlotte. As fans crowd the Queen City, city officials hope they use the new light-rail system to get to and from the arena.
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Duke Researchers Map Lemur’s Genomic Family Tree
UniversityTech: Better understanding of these animals found only in Madagascar could lead to better understanding of other primates.
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NCSU Discovery Could Lead to Microscopic ‘Smart’ Materials
UniversityTech: ‘Two-faced’ spheres could serve as microsensors or be used to target drug delivery.
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PPD to Buy Back $350M in Stock
Shares have increased 50 percent over past year.
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New Alliance Aims to Grow Life-Science Business in Eastern N.C.
BioEast Alliance, backed by N.C. Biotechnology Center, spells out strategies in $120,000 study. Group includes members from Edgecombe, Nash, Pitt, Wayne and Wilson counties.
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Addrenex, Investor Sciele Pharma Hope to Launch Hypertension Drug in 2009
RTP-based startup files new drug application with FDA. Partners also have launched Phase III trial of an ADHD drug.
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Duke Researchers Map Cancer’s Genetic ‘Support Network’
UniversityTech: genomics team uses new statistical techniques to look for relationships among sets of genes.
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PPD Founder Pledges $9M to Support UNC-CH Cancer Research
UniversityTech: Fred Eshelman, who gave $20 million to UNC in 2003, provides new funds for work at School of Pharmacy.
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RTI Hires Team of Researchers for Women’s Health Effort
San Francisco based group was part of University of California at San Francisco
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New Drug Shows Promise in Lessening Impact of Heart Attack Treatments
UniversityTech: Duke researchers say compound passes safety tests, could limit muscle damage in heart.
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GSK Gives Up Incentives Linked to Zebulon Plant Expansion
Drug giant was to receive nearly $1.4 million in grants for job creation at pharmaceutical production facility. GSK says it can’t guarantee that 200 newly created jobs will continue over several years.
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UNC Researchers Discover Possible ‘Overdrive’ to Trigger Cell Response
UniversityTech: Protein could be used in drugs, leading to new path for development. NIH helped fund research.
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Merger Complete, DARA BioSciences Goes Public
Raleigh-based drug development firm closes on merger with Massachusetts drug developer.
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Contract Pharma Firm Metrics Opens New Lab Space
Greenville-based company is doubling plant size in $18M expansion.
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Allen Roses, a Top Researcher in Genetics at GSK, is Returning to Duke
UniversityTech: Roses, who left Duke in 1997, will lead new Duke Drug Discovery Institute at university.
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RTI Names New Chief Medical Officer
Brad Walters, a former venture capitalist at Academy Funds, earned MBA at UNC’s Kenan-Flager.
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DuPont Partners with Durham Biotech Firm for Crop Development Efforts
Precision BioSciences, which utilizes technology developed at Duke, to focus on increasing harvests.
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Trimeris Gives in to Stockholder’s Demand for Two Board Seats
HealthCor, which is the largest shareholder in the biopharmaceutical firm, has been pressing the company to sell.
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PPD Acquires Russia-Based Contract Research Organization
Earnings report, new acquisition give boost to Wilmington company’s stock. PPD reports slight drop in earnings in 4Q but revenue, profits were up for year.
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Microneedles Can Deliver Medicine through Skin, Study Shows
UniversityTech: First peer-reviewed human study shows devices can deliver drugs. Georgia Tech, Kentucky researchers are involved in effort.
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Trimeris’ Largest Stockholder Steps Up Pressure for Company to Sell
In filings with SEC, N.Y. investment firm HealthCor also calls for two seats on board.
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BioMarck Receives FDA Approval for Phase II Trial of Lung Drug
RTP startup is utilizing technology developed at NCSU for drug that could treat cause, not just symptoms, of chronic obstructive respiratory disease.
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Athenix Lands Crop Research Deal with Syngenta
RTP firm will work with global agribusiness client to improve corn, soybean pest resistance.
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Don’t Tell Prominent Duke Doctor that Cancer Can’t Be Cured
Who’s Who: ‘We play to win. We want survivors,” says Dr. Henry Friedman, who has been featured on 60 Minutes.
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Scott Neuville Takes Over as CEO at Chesson Labs
Former CEO at Qualyst replaces David Terry, the CEO and a co-founder, who left startup in December.
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Hamner Institutes Researcher Lands $2.1M NIH Grant
Biology investigator Yin Chen will study development of mucous cells in search treatment for lung disorders. Chen holds a patent in mucous research.
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A Nobel Prize Doesn’t Change Oliver Smithies
Metro Magazine's Who's Who: Who’s Who: ‘I still have work to do,’ says UNC professor who was recognized for his genetic research. Retirement? ‘I’ll be retired when I get put 6 feet under,’ says 82-year-old scientist.
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‘On’ Switch in DNA Could Reveal Genetic Role in Development and Disease
UniversityTech: Duke researchers develop technology that permits scientists to look at entire genome, determine where gene regulation occurs.
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Quintiles Closes on Deal with New Investors
Although terms of investment haven’t been disclosed, media reports have said it topped $3 billion.
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LabCorp to Acquire Massachusetts CRO
Tandem Labs, which is based in Massachusetts, provides drug testing services.
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PPD Expands Lab Services Business to China
Wilmington-based contract research organization partners with Chinese firm.
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Biotech Center Hires Exec to Lead Centers for Innovation Effort
Mary Beth Thomas, a veteran with Small Business and Technology Development Center, fills new post.
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Quintiles to Open Office in Wilmington
Expansion is second announced in North Carolina over past year, in addition to new headquarters.
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LabCorp Licenses Duke Technology for Cancer Test
Blood-based test is designed for early detection of lung cancer.
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Serenex Partners with Non-Profit to Target Huntington’s Disease
CHDI will study Serenex molecules, which could combat central nervous system diseases.
